Summary

Bellingham + Stanley Single/Dual/Multiple Wavelength Polarimeter ADP600 Series with temperature control are designed for measuring optical rotation. They are especially suited for use by scientists wishing to measure chiral compounds and other optically active substances in the chemical, pharmaceutical and food sectors as well as for use in academic research.

• XPC Peltier temperature controlled
• Four decimal place resolution
• Conforms to USP/EP/BP/JP
• RFID user clearance
• High Definition touchscreen

Digital Polarimeters with Temperature Control
The ADP600 Series of polarimeters are available as multiple, dual, or single wavelength models, and with the ability to measure optical rotation to 4 decimal places across the visible spectrum as well as in the highly sensitive ultra-violet region. The series is split between 325, 365, 405, 436, 546, 589 & 633nm wavelengths depending on the model. Other wavelengths available on request, subject to interference filter availability.

The line of digital polarimeters features Xylem’s XPC temperature control technology. XPC technology replaces air temperature systems seen in previous models, providing for faster temperature stabilisation that is more representative of the sample than the air surrounding it.

The wide range of measuring capabilities, excellent temperature stability and high precision makes the ADP600 Series an excellent choice for laboratories within chemical, pharmaceutical and food sectors.

ADP600 Series Polarimeters accept standard size (30mm collar) XPC or special low volume leur taper polarimeter tubes facilitating measurement across optical path lengths between 5 and 200mm with tube diameters from 5 to 8mm being readable. Optional lids may be easily fitted to the ADP600 Series Polarimeters, facilitating sample tube entry and exit.

Polarimeters in line with Pharmacopoeia
The ADP600 Series Polarimeters have two pre-set operating temperatures being 20 and 25 °C in accordance with European and United States Pharmacopoeia respectively and other user temperatures between 20 and 30°C may be configured via the instrument user interface.

Peltier technology is intelligently applied to the sample tube of the new polarimeters so that measurement can be accurately made without the need of an external device such as a waterbath to control sample temperature.

Simple to use METHOD system
Integral to operational simplicity is the full colour, high definition, touchscreen graphical user interface. A menu structure featuring a METHODS system makes for one-touch calibration and instrument configuration; especially where the specific rotation of a number of samples is being analysed over a wide range of concentrations, path lengths, temperatures and wavelengths. A “Mean Method” is also available, allowing a number of readings to be taken from a production batch with the mean being calculated and recorded once the experiment has been completed. The Mean Method is ideal for pharmaceutical applications where compliance with pharmacopoeia is required.

RFID user clearance is standard in the ADP600 Series Polarimeters. The radio frequency technology first appeared in ADP400 Series Polarimeters, allowing users to sign in, personalise settings and help facilitate auditability all at the tap of a small fob key.

The ADP600 Series Polarimeters feature a secure “print to PDF” function that may be configured to operate in secure environments in accordance with FDA regulation 21 CFR Part 11 and importantly, the ADP600 Series polarimeters meet all of the requirements, including wavelength directives of British, United States, European and Japanese Pharmacopoeia.

You can learn more about the ADP600 Series' ability to comply with 21 CFR Part 11 in the following video.

Application

As many chemical compounds display this chiral characteristic, the measurement of optical rotation using a polarimeter is commonplace within the sugar, food, chemical and pharmaceutical manufacturing industries as a production control and quality assurance tool.Optical rotation is relative to the concentration of the dissolved sample and the length over which the measurement is taken and so it is common to quote chemicals as a specific rotation based on all the affecting factors, including temperature and wavelength. Concentration and purity may also be calculated by transformation.

Specification

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