Applied Scientific Instruments Co., Ltd.

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Applications and Industries : Pharmaceutical Development

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Applications and Industries

Pharmaceutical Development

Bettersize instruments provide test data of particle size distribution and the physical performance of powder so as to contribute to the whole process of pharmaceutical research, development and production. Grain size measurement attaches great importance to the pharmaceutical industry.

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Among pharmaceutical products, solid pharmaceutical preparations account for about 70% – 80%. They include powders, granulates, capsules, tablets, powder filling, suspensions, etc. The unit operations involved consist of smashing, grading, mixing, pelleting, drying, preforming, packaging, transportation and storage. In the preparation process, most solid preparations need to be further processed to improve their powder properties so as to meet the requirements of pharmaceutical quality and operation. The grain size analysis of pharmaceutical particles can also affect the release of the drug, thereby affecting its efficacy and toxicity. For example, if the pharmaceutical particles are too large, the drug will not be properly released, and if the pharmaceutical particles are too small, the drug will be released too quickly, which will increase toxicity and the possibility of side effects. Bettersize grain size analysis software can help you solve these problems. Our particle size analyzers, such as Bettersizer S3 Plus, Bettersizer 2600, etc, have been widely used in the pharmaceutical industry for grain size determination.

Bettersize instruments accurately measure particle size distribution, particle shape, powder flowability, tap density, bulk density and porosity. This assists in the whole process of pharmaceutical research, development and production.
 
BeNano 90 Zeta

The BeNano 90 Zeta is the latest generation of nanoparticle size and zeta potential analyzer designed by Bettersize Instruments Ltd. Dynamic light scattering (DLS)electrophoretic light scattering (ELS) and static light scattering (SLS) are integrated in the system to provide accurate measurements on particle size, zeta potential and molecular weight. The BeNano 90 Zeta is widely applied in academic and manufacturing processes of various fields including chemistry, chemical engineering, biology, pharmaceuticals, food, materials, et cetera.

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Bettersizer S3 Plus

The Bettersizer S3 Plus particle size and shape analyzer combines laser diffraction and dynamic image analysis in one instrument. It can measure the size and shape of particles  from 0.01 μm to 3500 μm. Its exceptional sensitivity for either ultrafine particles or oversized particles, and unsurpassed resolution, make it the most powerful size and shape analyzer for enthusiastic researchers who conduct top scientific research.

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Bettersizer 2600

The Bettersizer 2600 utilizes this laser diffraction technology. There are 92 photoelectric detectors to convert light signals from the scattering spectrum to electrical signals, which are transmitted into an intelligent software. By implementing the Mie scattering theory to the data and performing mathematical conversion, the complete particle size distribution can be derived.

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PowderPro A1

The physical properties of a powder pile are very important and need to be measured, the basic physical characteristics of powdered materials are practically significant in powder production, processing, transportation, storage and other applications. PowderPro A1 is mainly used for the analysis of powder physical characteristics by testing angle of repose and fall, angle of difference, angle of spatula, voidage, uniformity, cohesiveness, tapped density, bulk density, compressibility, dispersibility, flowability index, floodability index. PowderPro A1 was developed to obtain fast, simple, accurate, scientific test results for the physical properties of all these powders.

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PowderPro M1

PowderPro M1 is used to measure the physical properties of a powder pile. The basic physical characteristics of powdered materials are practically significant in powder production, processing, transportation, storage and other applications. For example, angle of repose and angle of fall should be considered while designing cone angle silos; tapped and bulk densities should be taken into account while designing packaging bags and barrels or during the production of tablets made from powdered raw materials,etc.

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